You are interested in | Biology homework help

Homework Assignment #8

Don't use plagiarized sources. Get Your Custom Essay on
You are interested in | Biology homework help
Just from $13/Page
Order Essay

Questions

1. You are interested in integrin activation and perform mutagenesis studies on

integrin. You find a mutant form of integrin which you call int-act, because the

int-act mutation causes the extracellular domain to exist always in an unfolded

state regardless of the presence or absence of ligand. When you determine the

sequence of int-act, you find that the mutation is in the intracellular domain of

integrin. Explain how this intracellular mutation could affect the conformation of

the extracellular domain of integrin.

2. Your friend, who is an engineering major, is interested in the mechanical

properties of extracellular matrix and wants to study how secreted collagen

molecules assemble into a collagen fiber. As part of his studies, he has been trying

to speed up the rate at which cells can produce the collagen protein and is

considering reducing the size of the propeptide that is attached to the collagen

chain such that it contains only the ER targeting sequence as well as the site for

cleavage of the propeptide. To his surprise, this modification causes collagen to

be degraded inside the cell. Can you explain why?

Place your order
(550 words)

Approximate price: $22

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
$26
The price is based on these factors:
Academic level
Number of pages
Urgency
Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.

Money-back guarantee

You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.

Read more

Zero-plagiarism guarantee

Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.

Read more

Free-revision policy

Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.

Read more

Privacy policy

Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.

Read more

Fair-cooperation guarantee

By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.

Read more